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Kruzik A, Fetahagic D, Hartlieb B, Dorn S, Koppensteiner H, Horling FM, et al

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If you have diabetes, consult your doctor before making any changes to your dosing schedule

This effect is associated with increased insulin signal transduction via phosphatidylinositol-3-OH kinase in the liver (but not in the skeletal muscle) and with reduced hepatic expression of the gluconeogenic genes, glucose-6-phosphatase and phosphoenolpyruvate kinase (German et al., 2009)

Here are important questions to ask yourself and discuss with your healthcare provider when deciding if metformin or Wegovy may be right for you: Are you comfortable with injections