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There's one more early finding worth holding onto, because it comes back later and it's an odd one

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"Synaptic plasticity in depression: Molecular, cellular and functional correlates"

Cellular energy & mitochondrial function studies

It was found that nasal mucosal toxicity and release of inflammatory and immunogenic mediators in plasma were negligible following nasal PenetraMax with or without insulin after acute and subchronic administration (Khafagy et al., 2013)