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However, as with any supplement or treatment, there's potential for side effects, especially when B12 is given in very high doses

It received GRAS (Generally Recognized as Safe) status for use as a food ingredient, which is a separate regulatory category

Mar 2020;9(Suppl 2):S206-S214

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The frequency of injections depends on individual needs and medical advice, but many people receive injections once a week if they are deficient