"At this time, there is no other medication like GLP-1s that consistently produces the degree of sustainable, clinically meaningful weight loss while improving metabolic markers," Dr
Thus, whilst the CVOTs provide valuable and supportive evidence of a benefit of GLP-1 RAs on HF in people with type 2 diabetes, additional trials are required to fully understand the magnitude and nature of such a potential effect, including if it applies to both prevention and treatment of the condition
10-14 The Diabetes Control and Complications Trial demonstrated a relationship between improved blood glucose control and increased risk of early worsening of DR, as well as between long-term risk reduction of DR with sustained blood glucose improvement
Your provider must evaluate your specific situation before deciding whether to pause or continue
If priced higher without clear superiority, uptake will be limited