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But clearly I think what the study showed was that this is a practice that's probably happening more often in Ontario than it should be happening." Silverstein, a recent graduate of medical school, remembered that little time was spent on the appropriate treatment of B12 deficiency

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The review article details analytical challenges such as heterophilic antibodies, pituitary HCG in peri and postmenopausal women, and variant forms that may cause false positive or negative results, guiding assay design and interpretation