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Building on this foundation, the gradual exploration of intelligent integration with biosensing technologies and controlled drug delivery systems should be pursued to lay the groundwork for personalized, adaptive, closed-loop therapy (57, 67)

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doi: 10.3389/fmed.2025.1633447 Received 22 May 2025 Accepted 11 August 2025 Published 29 August 2025 Volume 12 - 2025 Edited by Zili Xie, Icahn School of Medicine at Mount Sinai, United States Reviewed by Nina Fuller-Shavel, Synthesis Clinic, United Kingdom Ali Mussa, Omdurman Islamic University, Sudan Xiaoqing Cathy Cheng, Washington University in St

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