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Scheper V, Schmidtheisler M, Lasch F, et al

The 2026 Frontiers Review: A New Lens on Menopause and Allergy The Valerieva review synthesizes a growing body of evidence suggesting that menopause is not a passive endpoint of reproductive life but an active inflammatory and immunological transition

Conclusion Combination therapy with SGLT-2i and GLP-1RA may provide superior cardiovascular, weight, and Hemoglobin A1c outcomes versus monotherapy despite higher gastrointestinal adverse events

IV therapy requires sterile technique and licensed medical oversight