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Quick Take (TLDR) Mostly animal and in vitro data plus multiple very small uncontrolled human reports (knee pain case series n=16, interstitial cystitis pilot n=12, 2subject IV infusion) and no randomized controlled trials or published human pharmacokinetic profiles

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Symptoms of B12 deficiency can include extreme tiredness, lack of energy, pins and needles, muscle weakness, depression and problems with memory, understanding and judgement

When you use these peptides together they help the body fix itself in many ways at the same time

This also facilitates translational studies, in which experimental manipulations not possible in humans can provide greater insights into underlying biology