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While typically used for up to 6 months initially, longer-term use may be considered with appropriate add-back hormone replacement therapy (HRT) under specialist supervision

Results Nine clinical studies (one RCT, eight observational studies) with IIH patients receiving GLP-1 RAs were included

The trial enrolled adults with BMI of 30 or greater (or 27 or greater with dyslipidemia or hypertension) and used lifestyle intervention in both arms

For those who want the FDA-approved brands, Ozempic and Wegovy remain available through MEDVi as well, though at higher monthly costs

As of 2025, retatrutide has not been granted marketing authorisation by the MHRA or EMA and is not available through the NHS or licensed UK private prescribers