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All experiments were performed in accordance with the guidelines established by the National Institute of Health Guide for the Care and Use of Laboratory Animals and approved by the University of Texas Institutional Animal Care and Use Committee

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It contributes to avoid and prevent problems such as diabetes

ginseng , and various flavonoid-rich extracts, highlighting their functional robustness across diverse phytochemical classes ( For example, curcumin has been reported to restore VEGF expression and enhance angiogenesis in diabetic bone defect models, yet fails to exhibit similar pro-angiogenic effects in inflammation-driven environmentsunderscoring its strong microenvironmental dependency

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