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On the other hand, certain studies have demonstrated the overexpression of GLP-1R in brain tumors, embryonic tumors, gut and lung neuroendocrine tumors, including other endocrine tumors like Pheochromocytomas, raising concerns that existing GLP-1RAs can contribute to tumor growth in humans (Shilyansky et al., 2025

If this pattern is consistent and disruptive, discuss it with your prescribing clinician or trial team, as any dosing adjustments must follow the clinical trial protocol

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1 Introduction Obstructive sleep apnea syndrome (OSAS) is a chronic sleep-related breathing disorder characterized by recurrent upper airway collapse during sleep, leading to intermittent hypoxemia, sleep architecture disruption, and impaired daytime functioning (1, 2)

HL, hyperlipidemic