Microfluidics creates steep spatial and temporal solubility gradients, critical for uniform, well-defined nanoparticles (Nunziata et al., 2025)
Recent studies have shown that GLP-1(936) is particularly effective at low glucose concentrations, with its inhibitory effect being similar to that of GLP-1(7-36).241 GLP-1(936) retains its ability to inhibit glucagon secretion even after GLP-1R inactivation, suggesting that its mechanism of action may not be entirely dependent on the GLP-1R.241 GLP-1(936) promotes the undocking of secretory granules (SG) by inhibiting the entry of Ca2+ through voltage-gated Ca2+ channels
#Mounjaro gains the ground, so do #Ozempic, #Wegovy as well as many generic #semaglutide copies
GLP-1 is an incretin hormone that is produced and secreted by intestinal L-cells and in the central nervous system by neurons in the brainstem
Thyroid C-cell tumours In animal models, some GLP-1 drugs have been linked to C-cell tumours, but similar findings have not been clearly shown in humans so far