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The four peptides work synergistically. The components are associated with different proposed pathways

Pernicious anemia is caused by an absorption issue, not a lack of B12 intake

These include alterations in the monoaminergic system, changes in glutamatergic synaptic transmission, neuro-inflammation, alterations in the hypothalamic-pituitary-adrenocortical (HPA) axis, changes in brain-derived neurotrophic factor (BDNF), and hippocampal atrophy ( However, depression in AD is more specifically linked to deficits in certain brain regions and AD-related pathological changes

Changes in the perifollicular microenvironment may help explain age-related hair graying

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