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Common side effects include: Feeling sick (nausea) Vomiting Diarrhoea Constipation Indigestion or bloating These problems usually improve over time as your body becomes accustomed to the medicine

These diagnostics are underpowered with only three studies per comparison, and therefore do not allow reliable conclusions regarding the presence or absence of publication bias

With respect to the SOUL trial, oral semaglutide demonstrated a 14% reduction in MACE outcomes, independent of concurrent SGLT2 inhibitor use