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MLN0128, a Second-Generation mTOR Kinase Inhibitor, Disrupts Survival Signaling and Triggers Apoptosis in AML

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Research shows that SFN can restore NQO1 enzyme activity in leukemia cells carrying this polymorphism, which normally results in reduced activity ( Crucially, for the most extensively studied GST polymorphisms, the metabolic impact is profound and counterintuitive

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