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In dietinduced obese mice, NNMTi treatment significantly reduced liver weight, liver volume, and hepatic triglyceride levels, alleviated hepatic steatosis and inflammatory infiltration, downregulated inflammatory factors (such as TNF and IL6) and lipogenic genes (such as FAS), and upregulated lipolytic genes (such as ATGL) in the liver

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EBioMedicine 53 , 102696 (2020)

Certain medications may also interfere with absorption and cause deficiency, in particular, medicines prescribed for heartburn, antibiotics, blood pressure medicine, cholesterol-lowering drugs, diabetes medications and antipsychotic drugs

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