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If you notice particulate matter, cloudiness, or discoloration in your semaglutide pen or vial, do not use the medication

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Keep the medication in its original carton to protect it from light until ready for use

A short intake questionnaire cannot replace a comprehensive medical assessment that includes health history review, medication reconciliation, laboratory evaluation, and cardiovascular risk screening

And without the continued downward trajectory that motivated continued use, exploring alternatives with different mechanisms becomes an appealing strategy to break through stalled progress