A summary of the baseline characteristics is presented in Table 2 [additional characteristics are provided in Table S1 in the electronic supplementary material (ESM)]
They are not suitable for patients with multiple endocrine neoplasia syndrome type two
Instead, they get confusion about what is working, potential side effects from unknown sources, and wasted money on compounds they may not need
call 999 if accompanied by severe systemic illness) Signs of gallbladder disease : Right upper quadrant pain, jaundice, fever (contact GP urgently or NHS 111) Symptoms of thyroid tumours : Neck lump, hoarseness, difficulty swallowing (rare, but GLP-1 agonists carry a theoretical risk based on animal studies) [15] [21] Allergic reactions : Rash, swelling, difficulty breathing (call 999 for severe reactions with breathing difficulties) Acute kidney injury : Reduced urine output, swelling, confusion (contact GP urgently or NHS 111
Favus et al