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doi:10.31128/AJGP/04-23-6805

Heart failure therapy by GLP-1RAs Although a meta-analysis of large-scale clinical trials suggested that GLP-1RAs reduce heart failure hospitalizations (HHF) by approximately 10% in patients with diabetes at high cardiovascular risk [22, 23], the treatment effects on the risk of HHF in individual trials other than AMPLITUDE-O were not significant (Tables 1, 2)

OFA and compounder FarmaKeio sued the agency, arguing that this was rulemaking dressed up as adjudication in violation of the Administrative Procedure Act (APA)