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Okun The New England Journal of Medicines recent publication of a randomized study of a GLP-1 agonist originally designed for diabetes, but applied to Parkinson's disease, has led to a flurry of excitement and to a mountain of questions

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In animal work, raising NAD has been observed to shift healthspan markers in mice, with reported changes in mitochondrial function and sirtuin-mediated DNA repair (Mills et al., 2016)

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