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doi: 10.1038/1821670a0 23 MitchellJ

These medications are often prescribed for people with type 2 diabetes to help control blood sugar levels or for patients seeking weight loss

It seems possible that oxidation of these thiols to disulfides, under a mechanism of oxidative stress, would increase the affinity of SARS-CoV and SARS-CoV-2 S proteins for the ACE2 receptor, and therefore, increase the severity of COVID-19 infection [30, 60]