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ALW-II-4127 significantly alleviates atherosclerosis in ApoE -/- mice by reshaping gut microbiota and modulating bile acid metabolism, reducing plaques and increasing collagen and smooth muscle cell content (178)

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GLP-1R agonists exert broad antiinflammatory effects in multiple peripheral organs, including the central nervous system, lungs, cardiovascular system, liver, intestine, kidneys, and joints

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