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Targeting of XJB-5131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease

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As an anti-aging ingredient, retinol works by stimulating cellular turnover for firm and youthful skin, but the drawback is that the active can make your skin more sensitive to UV damage and other irritants

In this context, using a previously reported -helical peptide as a template sequence (Behera et al., 2022), this study discusses the rational computational design and in silico evaluation of an -helical peptide (SR18: 18 aa) as a potent agonist of GLP-1R, with native GLP-1 and Semaglutide serving as references