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Tendon and ligament repair, gastrointestinal mucosal healing, soft tissue recovery, and neuroprotective signaling are all supported by reproducible rodent and in vitro work, while the human evidence remains limited to one unpublished Phase 2 IBD trial and a small number of preliminary studies

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These effects were achieved through direct inhibitory actions on prostatic GH-RH receptors, as evidenced by significant tissue-specific reductions in levels of NF-B/p50, cyclooxygenase-2, and androgen receptors, and changes in the expression of over 90 genes related to growth, inflammation, and signal transduction

Consequently, it puts the liver, lungs, kidneys, and other organs far from harm