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About Me Let's get to know each other Im Alexandros Manifavas, as a Senior System Administrator with extensive experience in the information technology and services industry, I am well-versed in a variety of technical areas including device management solutions, Azure, Active Directory, MECM, Intune, M365, and PowerShell

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The intestinal microbiota of IBD patients is characterized by an increase in pro-inflammatory bacteria and altered expression of multiple cytokines [95, 97, 98]

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The tryptophan-kynurenine pathway functions as a stress-activated metabolic system that diverts tryptophan from serotonin synthesis toward kynurenic acid production, which acts as a glutamate receptor antagonist and may contribute to anxiety pathophysiology through altered glutamatergic neurotransmission (Butler et al., 2022)