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The theory of the origin of sleep which has gained the widest credence is the one that attributes it to anemia of the brain The idea behind this supposition has been that, as the day draws to an end, the circulatory mechanism becomes fatigued, the vasomotor center exhausted, the tone of the blood vessels deficient, and the energy of the heart diminished, and thus is the circulation to the cerebral arteries lessened. NATURE, May 5th, 1898

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At ~504 Da molecular weight with only two amino acid residues (Tyr-Ile core), it falls below the typical size range of bioactive peptides

Some individuals may require more than one vial per month

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