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Description

A GLP-1 Analog Lowers ER Stress and Enhances Protein Folding to Ameliorate Homocysteine-Induced Endothelial Dysfunction. Acta Pharmacologica Sinica, vol

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Uehara T, Choong C-J, Nakamori M, Hayakawa H, Nishiyama K, Kasahara Y, Baba K, Nagata T, Yokota T, Tsuda H et al (2019) Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting -synuclein as a novel therapy for Parkinsons disease

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Symptoms include: Fatigue and weakness Chronic burning in the throat and nasal passages Coughing, wheezing, and shortness of breath Loss of balance Depression and/or anxiety Skin rashes Eye irritation or tearing of the eyes Headache and/or light sensitivity Hearing loss Heightened sensitivity to chemicals and foods Irregular heartbeat Morning stiffness and/or joint pain Muscle weakness Sleep problems Poor memory, difficulty finding words Slower reaction time Vision changes Difficulty concentrating Abdominal pain, diarrhea, and/or bloating Unusual skin sensations, tingling, and numbness Increased urinary frequency or increased thirst Disorientation and/or dizziness Static shocks or metallic taste in the mouth Additionally, mycotoxin toxicity is linked explicitly to neurological symptoms, with patients reporting cognitive, emotional, and behavioral effects

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Glutathione S-transferase pi mediates MPTP-induced c-Jun N-terminal kinase activation in the nigrostriatal pathway

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