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Some even suggest that they may worsen the neurological damage associated with vitamin B12 deficiency ( Additionally, some scientists are concerned that a high intake of folic acid a synthetic form of vitamin B9 may cause health problems

(2003) reported similar results in mice

The mechanism involved is not known, but the cardiovascular actions will importantly support the future use of GLP-1 receptor agonists, which are already generally recommended as second line therapies for patients with metformin failure (120)

Why it might be helpful: Eating significantly less food can lead to nutrient deficiencies over time, particularly if you are not consciously focusing on nutrient-dense choices