Dehydration and Electrolyte Changes as Contributing Factors Semaglutide-induced nausea and reduced food intake can lead to inadequate hydration and electrolyte depletion, both of which can trigger or worsen muscle cramps and back tension
Nature 266:565567 Xu D, Trmulot L, Yang Z, Mhamdi A, Chtel-Innocenti G, Mathieu M, Espinasse C, Van Breusegem F, Vanacker H, Issakidis-Bourguet E, Noctor G (2025) Cytosolic monodehydroascorbate reductase 2 promotes oxidative stress signaling in Arabidopsis
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Some are approved for diabetes, some for chronic weight management, and some may be discussed off-label based on the providers clinical judgment