Ozempic, Mounjaro, and Wegovy are now widely recognized, particularly among individuals managing diabetes and obesity
Conversely, our analysis suggests that use of GLP-1 RAs is unlikely to be cost-effective from a healthcare or societal perspective (based solely on their cardiovascular benefits) in either population at current prices
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Limited generic competition (patents) keeps prices high
Our hypothalamic transcriptomics data revealed upregulated receptors, including calcitonin receptor, NPY2 receptor, and MC4R, providing insights into the neural mechanisms underlying metabolic dysregulation in Bbs5 / mice