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Globally, the critical pathogens associated with AMR-based deaths include Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa 31,32

The ALDH1B1 (commonly identified as ALDHX) encoded aldehyde dehydrogenase has also been shown to contribute to mitochondrial oxidation of acetaldehyde derived from ethanol

ROS deregulate the redox homeostasis and promote tumor formation by initiating an aberrant induction of signaling networks that cause tumorigenesis [9]

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