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On GLP-1 therapy, this normal processing time is further prolonged , which can make protein-heavy meals feel unusually heavy or uncomfortable, contributing to the sensation that food is lingering. High-fat meals and physiologic slowing of digestion Dietary fat slows gastric emptying through normal physiologic feedback

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The consistency of modeling and experimental results for the most efficient reactions but not the others may indicate the scaling limitations of model predictions to experimental data and/or performance of the model itself