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18 Endothelial dysfunction is a characteristic feature of patients with atherosclerosis and more recent studies indicate that it may predict long-term atherosclerotic disease progression as well as cardiovascular event rate

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J Clin Invest 2014;124:4473-88.ArticlePubMedPMC 58

Patients with a personal or family history of bleeding disorders, those taking anticoagulants, or individuals experiencing unexpected bruising from minor trauma should notify their healthcare provider before starting semaglutide therapy

The slowed digestion also helps decrease blood sugar spikes, and the satiety effect of GLP1- agonists reduces food intake, appetite, and hunger