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In a study conducted on Japanese patients with T2DM, those who received tirzepatide doses ranging from 5 to 15 mg for 52 weeks experienced a significant decrease in HbA1c levels by 2.43.02%

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Another observational study from 2024, titled Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide, noted an association between semaglutide, the main drug in Ozempic, and Non - Arteritic Ischemic Optic Neuropathy (NAION), an ocular disease which can cause permanent and severe vision loss