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It was demonstrated that in the spinal cord of the SOD1-G93A ALS mouse model, the mitochondrial receptor SQSTM1/p62 is recruited to the mitochondrial surface, where it activates mitophagy, whereas knockdown of the Parkin gene reduces the loss of motor neurons, thereby delaying the progression of disease in SOD1-G93A mice (Palomo et al., 2018)

Edinburgh: Elsevier, 2017:205-14

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We built this guide the way we wish more supplement brands would: by telling you where our products fit and, just as clearly, where they do not

10.1016/j.cell.2013.05.027 Cell 76 ChangJ.RimandoA.PallasM.CaminsA.PorquetD.ReevesJ.et al (2012)