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Results Interim analysis The trial was halted early in October 2023 after the DSMB performed an interim analysis after 570 events had accrued, and stopping rules were met
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While our data demonstrated clear efficacy for both compounds in reducing alcohol interoceptive effects across the tested dose ranges, it will be important in future work to assess efficacy following repeated treatment and to directly compare potential advantages in terms of efficacy, side-effect profiles, and tolerability
Participants who took the stronger dose lost about 19% of their body weight, or about 47 pounds on average
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