Results Study selection The search retrieved 432 records from bibliographic databases (PubMed/MEDLINE 98, Embase 152, Web of Science 84, Scopus 86, Cochrane CENTRAL 12) and 28 additional records from other sources
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At 24 weeks (the last point before people taking a placebo were eligible to switch to orforglipron), people taking a placebo had roughly gained 20 pounds back on average, no matter which drug they were taking originally