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According to Exley followed by Bolognin et al., only aluminum, but not copper or iron, is capable of triggering amyloid precipitation and APP and tau181 protein overproduction [20, 21]

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Vitamin B12 is required for creating new red blood cells

Additionally, electrophysiological experiments have shown the direct effects of B vitamins on pain transmission pathways in the spinal cord and thalamus, which explains the observed reduction or loss of pain sensation in clinical patients