dpp4 and glp 1 used together Cleavage site of GLP-1 protein by (The yellow colour marking DPP4 degrade the GLP1 and

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Following local radiotherapy combined with systemic anlotinib treatment, the patient achieved prolonged progression-free survival (PFS) exceeding 32 months

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The mutants exhibited a significant effect on the nanobodies stability, as evidenced by the Cartesian ddG values ranging from -8.9 kcal/mol to 63.8 kcal/mol for PV2 and 9.4 kcal/mol to 73.3 kcal/mol for PV3