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Results Emulating pivotal cardiovascular outcome trials and expanding populations To validate our analytical framework, we emulated the cardiovascular outcome trials SUSTAIN-6 and SURPASS-CVOT using three national claims databases from the USA

But Dr Simon Cork, a senior lecturer in physiology at Anglia Ruskin University in Cambridge, told MailOnline: 'This is essentially a sign that the drugs are working at reducing weight.' He said: 'The buttocks are one of the areas of the body where we deposit excess fat, more so in some people than others

You may need to delay your next dose increase or temporarily reduce your dose

Immune system function The state of an individual's immune system plays a significant role in determining the likelihood and severity of injection site reactions

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