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Basu S, Whiteman M, Mattey DL, Halliwell B

While the peptides activation of ENC-alpha in the lungs is a good thing in pneumonia where fluid literally interferes with breathing, the investigators were concerned that activating ENaC-alpha in the kidneys might disturb normal sodium retention, which is important to the kidneys role in blood pressure regulation

Retrieved November 12, 2022

Toxicol In Vitro 41 , 214222 (2017)

The answer comes down to what "sterile" and "0.9%" actually require at a pharmaceutical level and why falling short of either standard creates contamination risk that is invisible until something goes wrong