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The analysis of the tissues showed a significant decrease in proteins that help form tight junctions in the BBB

The peptide also enhances the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), critical molecules for neuronal survival and plasticity

After complete transection 5 mm proximal to calcaneal insertion, daily BPC-157 (10 g, 10 ng, or 10 pg per kg body weight) was administered starting 30 minutes post-surgery