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10.1161/CIRCULATIONAHA.107.739938 4 BaraleC.BuraccoS.CavalotF.FrascaroliC.GuerrasioA.RussoI

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Concurrently, the use of GLP-1 RAs in patients with metabolic dysfunction-associated steatotic liver disease (MASLD) has been associated with a clinically meaningful reduction in all-cause mortality, major cardiovascular events, and progression to metabolic dysfunction-associated steatohepatitis (MASH)

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[29] which showed great similarity to the novel class of large GDH enzymes known as the L_180 class [18]