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Generally acting as a tumor suppressor, ChaC2 decreases GSH levels in tumor cells, instigates mitochondrial apoptosis and autophagy via UPR and hinders tumor cell proliferation and migration in vitro and in vivo (79)

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One STEP trial showed an average loss of about 10% with Wegovy versus 3% with placebo over 68 weeks

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[9] Krahmer N, et al

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