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produced PQQ as pyrroloquinoline quinone disodium (product named BioPQQ , C 14 H 10 N 2 Na 2 O 11 , formula weight: 428.22 amu) by fermentation

These findings establish a consensus-driven and transferable computational framework for chemotype-diverse agonist discovery at conformationally flexible GPCR targets, and revealed a pentapeptide with GLP-1-like efficacy as a promising lead for next-generation small peptide therapeutics

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Interestingly, we found that succinate accumulated only in Gclc- deficient B cells and not in Gclc- deficient effector T cells nor Tregs 43,44

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