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Research indicates that colonizing adult GF mice with a conventional microbiota significantly elevates their serum IGF-1 levels, correlating with heightened levels of the bone formation marker P1NP (N-terminal propeptide of type I collagen) and elevated bone formation rates, thereby facilitating both radial and longitudinal bone growth
PMID: 26458565
"Microdosing" is not part of the standard authorised Wegovy dose schedule
Depletion of LAG-3(+) T cells translated to pharmacology and improvement in psoriasis disease activity: a phase I randomized study of mAb GSK2831781
Dosing flexibility Wegovy follows a fixed dose escalation schedule, typically progressing to the maintenance dose of 2.4 mg over 16-20 weeks
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