Each technology offers potential benefits like improved bioavailability or better absorption sites, but also faces challenges such as manufacturing difficulties, high costs, and regulatory hurdles
101 SunL.WangY.SongY.ChengX.XiaS.RahmanM.et al (2015)
To produce transitory aqueous conduits MN was designed, which crossed the skin
One clinical trial enrolled 73 eligible participants with normal but low B12 levels and inadequate initial response to selective serotonin reuptake inhibitors (SSRIs), who were randomly assigned to either a treatment group (antidepressants combined with B12 injections, n = 34) or a control group (antidepressants alone, n = 39)
Kratzsch J, Lammert A, Bottner A, Seidel B, Mueller G, Thiery J et al