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Concepts such as stimuli-responsive nanocarriers, organ-on-chipguided formulation screening and digital twinassisted personalization have been demonstrated at the experimental or pilot level but not yet at industrial scale

have demonstrated that butyrate contributes to epithelial barrier tightness through the inhibition of iron-dependent prolyl hydroxylase enzymes, leading to the stabilization of hypoxia-inducible factor (HIF) (Ornelas et al., 2023)

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29.3%), MALE rate (0.8% vs

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