Diabetes can also weaken the immune system and cause nerve damage that affects bladder control, leading to incomplete bladder emptying
There are several reasons people might want to switch: Weight loss plateaus after a few months on semaglutide Gastrointestinal side effects like nausea or constipation that are not manageable Desire for better glucose control Personal goals (e.g., prefer faster weight loss progress ) In my practice, the most common reasons I recommend patients to switch medication is 1) they are having uncomfortable or unmanageable side effects from semaglutide including heart burn, nausea, constipation or 2) their weight loss starts to plateau before they reach their weight loss goals
However, this does not definitively exclude the possibility of muscle-related symptoms in individual patients, as clinical trials may not capture all real-world experiences, particularly uncommon or delayed adverse effects
Most side effects were concentrated in the dose-escalation phase, but for a meaningful subset of people they persist at maintenance doses
As availability has increased and new options have emerged, weve made the decision to end our plans coverage for GLP-1s for weight loss, the spokesperson said