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Finally, the role of coenzyme Q 10 as an antioxidant is also exemplified by recent evidence showing that mitochondrial coenzyme Q 10 deficiency causes an increased production of mitochondrial superoxide radical anion (O 2 ) which might be driving insulin resistance in adipose and muscle tissues (7)

Synergy Between Glutathione and Vitamin C While both antioxidants are effective individually against oxidative stress, their combined efforts can be particularly potent

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Because of ubiquitination and subsequent proteolysis, Nrf2 turns over rapidly with a half-life of 715 min, which increases to 30100 min in the presence of oxidative or electrophilic stress (McMahon et al

These agents not only augment insulin secretion but also suppress glucagon release, thereby providing a more holistic approach to glycemic control